How to Treat Nose Polyps Without Surgery ???
Nose Polyps has a complex andmultifactorial pathogenesis with a heterogeneous inflammatoryprofile. Proteomic analysis of nasal mucus may enable furtherunderstanding of protein abundances and biologic processespresent in CRS and its endotypes compared with in healthypatients. Nose Polyps endotypes and pathophysiologyhave evolved over time, with hypotheses suggesting theinvolvement of pathogen dysbiosis, immune dysregulation,and environmental factors.1Dysfunction of the epithelial barrierin patients with CRS has also been suggested as a key event inthe disease process, although the precise mechanism by whichthis occurs remains unknown. Recent work in our departmenthas demonstrated that locally produced mucus may have animportant effect on the nasal epithelial barrier, with mucusfrom healthy patients shown to be associated with improvedbarrier integrity and mucociliary clearance, whereas mucusfrom patients with Nose Polyps was found to be associated withincreased mucosal inflammation. Ele...